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School Of Medicine School Of Medicine

School Of Medicine School Of Medicine

School Of Medicine School Of Medicine

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Profiling Children with Neural Tube Defects at the University Teaching Hospital, Lusaka, Zambia

ABSTRACT

Background: Neural tube defects (NTDs) are the commonest disabling congenital defects which affect about 300,000 infants each year. In developing countries like Zambia, these defects are unrecognized and under reported. Therefore, the aim of this study was to determine the profile of children with NTDs at the University Teaching Hospital (UTH) in Lusaka.

Methodology: A retrospective review of medical records of children with NTDs who were who were admitted at the UTH between January and December, 2010 was done. Data was collected using a data extraction sheet and descriptive analysis was done using Statistical Package for Social Science (SPSS) version 20.

Results: A total of 101 medical records were identified and 50 of them were for children with NTDs giving a prevalence rate of 50%. The sample of children with NTDs had more boys (58%) than girls (42%). The majority of the children were from Lusaka province with 28%, while the minority were from North-Western and Copperbelt provinces with 2% each. The profile showed that many children (78%) presented with Spina Bifida (SB), with encephalocele (20%) and lastly one with both SB and encephalocele (2%). Myelomeningocele was the most common type of SB (44%) while the lumbar region was the commonest site (52%). Occipital encephalocele (60%) was the commonest compared with the nasal (30%) and frontal (10%).

Conclusion: The majority of the children with NTDs admitted at the UTH were from Lusaka province and SB was the most common type of NTDs. Myelomeningocele was the most common presentation while the lumbar region was the most common site. Occipital encephalocele was the commonest site compare with other regions.

Keywords: Neural tube defects, spina bifida, meningocele, myelomeningocele, encephalocele, Zambia

Micah Simpamba, Margaret M. Mweshi and Patricia M. Struthers. Profiling Children with Neural Tube Defects at the University Teaching Hospital, Lusaka, Zambia. Journal of Preventive and Rehabilitative Medicine, Vol. 1, No. 1, 2018, pp. 12-18. doi: 10.21617/jprm.2018.0101.2

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